全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR04283G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EpCAM Antibody (C-term).
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分子量 |
34932 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
200-229 aa
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靶點(diǎn) |
This EpCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-229 amino acids from the C-terminal region of human EpCAM.
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亞型 |
Rabbit Ig
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通用名 |
GA733-2, M1S2, M4S1, MIC18, TACSTD1, TRO
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基因ID |
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UniProt ID |
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功能 |
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
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總結(jié) |
This gene encodes a carcinoma-associated antigen and is amember of a family that includes at least two type I membraneproteins. This antigen is expressed on most normal epithelial cellsand gastrointestinal carcinomas and functions as a homotypiccalcium-independent cell adhesion molecule. The antigen is beingused as a target for immunotherapy treatment of human carcinomas.Mutations in this gene result in congenital tufting enteropathy.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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