ZFP36L2 Antibody (Center)

APR04237G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR04237G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ZFP36L2 Antibody (Center)

品牌	Leading Biology	貨號	APR04237G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZFP36L2 Antibody (Center).
分子量	51063 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	166-193 aa
靶點(diǎn)	This ZFP36L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the Central region of human ZFP36L2.
亞型	Rabbit Ig
通用名	BRF2, ERF2, RNF162C, TIS11D
基因ID	678
UniProt ID	P47974
功能	mRNA-binding protein that plays a key role in self- renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit- erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation (By similarity).
總結(jié)	This gene is a member of the TIS11 family of earlyresponse genes. Family members are induced by various agonists suchas the phorbol ester TPA and the polypeptide mitogen EGF. Theencoded protein contains a distinguishing putative zinc fingerdomain with a repeating cys-his motif. This putative nucleartranscription factor most likely functions in regulating theresponse to growth factors.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	ZFP36L2 Antibody (Center) (Cat. APR04237G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ZFP36L2 antibody detected the ZFP36L2 protein (arrow). ZFP36L2 Antibody (Center) (Cat. APR04237G) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ZFP36L2 antibody detected the ZFP36L2 protein (arrow).
說明書	Product Datasheet Protocol
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