品牌 |
Leading Biology | 貨號 |
APR04147G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRPC1 Antibody (C-term).
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分子量 |
91212 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
765-793 aa
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靶點 |
This TRPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 765-793 amino acids from the C-terminal region of human TRPC1.
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亞型 |
Rabbit Ig
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通用名 |
TRP1
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基因ID |
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UniProt ID |
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功能 |
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
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總結(jié) |
TRPC1 belongs to the transient receptor potential (TRP)superfamily of cation channels. TRP cation channels are involved indiverse physiologic processes, including receptor- andstore-operated Ca(2+) entry, mineral absorption, and cell death.They also function as sensors for pain, heat, cold, sound, stretch,and osmotic changes (Zhang et al., 2009 [PubMed19193631]).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Anti-TRPC1 Antibody (C-term) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 91 kDa Blocking/Dilution buffer: 5% NFDM/TBST. TRPC1 Antibody (C-term) (Cat. APR04147G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TRPC1 antibody detected the TRPC1 protein (arrow). |
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說明書 |
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數(shù)量 |
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