DSC3 Antibody (C-term)

APR04137G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR04137G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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DSC3 Antibody (C-term)

品牌	Leading Biology	貨號	APR04137G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DSC3 Antibody (C-term).
分子量	99969 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	822-850 aa
靶點(diǎn)	This DSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of human DSC3.
亞型	Rabbit Ig
通用名	CDHF3, DSC4
基因ID	1825
UniProt ID	Q14574
功能	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
總結(jié)	The protein encoded by this gene is a calcium-dependentglycoprotein that is a member of the desmocollin subfamily of thecadherin superfamily. These desmosomal family members, along withthe desmogleins, are found primarily in epithelial cells where theyconstitute the adhesive proteins of the desmosome cell-celljunction and are required for cell adhesion and desmosomeformation. The desmosomal family members are arranged in twoclusters on chromosome 18, occupying less than 650 kb combined.Alternative splicing results in two transcript variants encodingdistinct isoforms.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	Western blot analysis of lysate from A431 cell line, using DSC3 Antibody (C-term)(Cat. APR04137G). APR04137G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
說明書	Product Datasheet Protocol
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