全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR04126G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse Nlrp6 Antibody (Center).
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分子量 |
97402 Da
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細胞定位 |
Antigen Cellular Localization:
Isoform 1: Cytoplasm. Cell membrane. Nucleus membrane
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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免疫原 |
343-372 aa
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靶點 |
This Mouse Nlrp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the Central region of mouse Nlrp6.
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亞型 |
Rabbit Ig
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通用名 |
Nalp6, Pypaf5
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基因ID |
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UniProt ID |
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功能 |
May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Isoform 1 binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor. Isoform 2 binds both arginine- vasopressin and angiotensin II and acts as an angiotensin II/vasopressin receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation.
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總結(jié) |
Nlrp6 may mediate activation of CASP1 via ASC and promote activation of NF-kappa-B (By similarity).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:2000
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圖像 |
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說明書 |
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數(shù)量 |
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