全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR04112G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DND1 Antibody (Center).
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分子量 |
38687 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3 (By similarity).
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
198-226 aa
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靶點(diǎn) |
This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human DND1.
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亞型 |
Rabbit Ig
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通用名 |
RBMS4
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基因ID |
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UniProt ID |
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功能 |
RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).
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總結(jié) |
This gene encodes a protein that binds tomicroRNA-targeting sequences of mRNAs, inhibiting microRNA-mediatedrepression. Reduced expression of this gene has been implicated intongue squamous cell carcinoma. Two pseudogenes of this gene arelocated on the long arm of chromosome 17.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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