全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR04026G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse Frk Antibody (C-term).
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分子量 |
58844 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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免疫原 |
464-491 aa
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靶點 |
This Mouse Frk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-491 amino acids from the C-terminal region of mouse Frk.
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亞型 |
Rabbit Ig
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通用名 |
Bsk, Iyk
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基因ID |
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UniProt ID |
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功能 |
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
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總結(jié) |
Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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