USP4 Antibody (N-term)

APR03989G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03989G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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USP4 Antibody (N-term)

品牌	Leading Biology	貨號	APR03989G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality USP4 Antibody (N-term).
分子量	108565 Da
細胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus Note=Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor The relative amounts found in the nucleus and cytoplasm vary according to the cell type.
宿主	Rabbit
種屬反應性	Human
免疫原	1-30 aa
靶點	This USP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USP4.
亞型	Rabbit Ig
通用名	UNP, UNPH
基因ID	7375
UniProt ID	Q13107
功能	Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.
總結(jié)	Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. Plays a role in the regulation of quality control in the ER.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
圖像	USP4 Antibody (N-term) (Cat. APR03989G) western blot analysis in human uterine tumor tissue lysates (35ug/lane).This demonstrates the USP4 antibody detected the USP4 protein (arrow). USP4 Antibody (N-term) (APR03989G)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of USP4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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