TPX2 Antibody (Center)

APR03973G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR03973G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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TPX2 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR03973G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TPX2 Antibody (Center).
分子量	85653 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	419-448 aa
靶點(diǎn)	This TPX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the Central region of human TPX2.
亞型	Rabbit Ig
通用名	C20orf1, C20orf2, DIL2, HCA519
基因ID	22974
UniProt ID	Q9ULW0
功能	Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
總結(jié)	TPX2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	TPX2 Antibody (Center) (Cat. APR03973G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TPX2 antibody detected the TPX2 protein (arrow).
說明書	Product Datasheet Protocol
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