品牌 |
Leading Biology | 貨號 |
APR03951G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CSTA Antibody (C-term).
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分子量 |
11006 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
69-98 aa
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靶點(diǎn) |
This CSTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the C-terminal region of human CSTA.
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亞型 |
Rabbit Ig
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通用名 |
STF1, STFA
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基因ID |
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UniProt ID |
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功能 |
This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis.
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總結(jié) |
The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins, and kininogens. This gene encodes astefin that functions as a cysteine protease inhibitor, formingtight complexes with papain and the cathepsins B, H, and L. Theprotein is one of the precursor proteins of cornified cell envelopein keratinocytes and plays a role in epidermal development andmaintenance. Stefins have been proposed as prognostic anddiagnostic tools for cancer.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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圖像 |
CSTA Antibody (C-term) (Cat. APR03951G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CSTA antibody detected the CSTA protein (arrow). Western blot analysis of CSTA (arrow) using rabbit polyclonal CSTA Antibody (C-term) (Cat. APR03951G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CSTA gene. CSTA Antibody (C-term) (APR03951G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSTA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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