MAS1 Antibody (C-term)

APR03929G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR03929G		100 μl / ￥4950

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MAS1 Antibody (C-term)

品牌	Leading Biology	貨號(hào)	APR03929G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAS1 Antibody (C-term).
分子量	37465 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	285-314 aa
靶點(diǎn)	This MAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human MAS1.
亞型	Rabbit Ig
通用名	MAS
基因ID	4142
UniProt ID	P04201
功能	Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
總結(jié)	The structure of the MAS1 product indicates that itbelongs to the class of receptors that are coupled to GTP-bindingproteins and share a conserved structural motif, which is describedas a '7-transmembrane segment' following the prediction that thesehydrophobic segments form membrane-spanning alpha-helices. The MAS1protein may be a receptor that, when activated, modulates acritical component in a growth-regulating pathway to bring aboutoncogenic effects.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	MAS1 Antibody (C-term) (Cat. APR03929G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MAS1 antibody detected the MAS1 protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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