品牌 |
Leading Biology | 貨號(hào) |
APR03924G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRSS8 Antibody (Center).
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分子量 |
36431 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Prostasin: Cell membrane; Single-pass membrane protein Prostasin heavy chain: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
190-219 aa
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靶點(diǎn) |
This PRSS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human PRSS8.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
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總結(jié) |
This gene encodes a trypsinogen, which is a member of thetrypsin family of serine proteases. This enzyme is highly expressedin prostate epithelia and is one of several proteolytic enzymesfound in seminal fluid. The proprotein is cleaved to produce alight chain and a heavy chain which are associated by a disulfidebond. It is active on peptide linkages involving the carboxyl groupof lysine or arginine.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
PRSS8 Antibody (Center) (Cat. APR03924G) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PRSS8 antibody detected the PRSS8 protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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