品牌 |
Leading Biology | 貨號(hào) |
APR03866G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality C9 Antibody (Center).
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分子量 |
63173 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
191-220 aa
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靶點(diǎn) |
This C9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-220 amino acids from the Central region of human C9.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
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總結(jié) |
This gene encodes the final component of the complementsystem. It participates in the formation of the Membrane AttackComplex (MAC). The MAC assembles on bacterial membranes to form apore, permitting disruption of bacterial membrane organization.Mutations in this gene cause component C9 deficiency. [provided byRefSeq].
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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圖像 |
Anti-C9 Antibody (Center) at 1:1000 dilution + human liver lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 63 kDa Blocking/Dilution buffer: 5% NFDM/TBST. C9 Antibody (Center) (Cat. APR03866G) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the C9 antibody detected the C9 protein (arrow). C9 Antibody (Center) (APR03866G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of C9 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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