品牌 |
Leading Biology | 貨號(hào) |
APR03853G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP8 Antibody (N-term).
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分子量 |
53412 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasmic granule. Secreted, extracellular space, extracellular matrix. Note=Stored in intracellular granules
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
56-84 aa
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靶點(diǎn) |
This MMP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMP8.
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亞型 |
Rabbit Ig
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通用名 |
CLG1
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基因ID |
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UniProt ID |
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功能 |
Can degrade fibrillar type I, II, and III collagens.
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總結(jié) |
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is stored in secondary granules within neutrophils and isactivated by autolytic cleavage. Its function is degradation oftype I, II and III collagens. The gene is part of a cluster of MMPgenes which localize to chromosome 11q22.3.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
MMP8 Antibody (N-term) (Cat. APR03853G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MMP8 antibody detected the MMP8 protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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