品牌 |
Leading Biology | 貨號(hào) |
APR03851G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP16 Antibody (C-term).
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分子量 |
69521 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform Long: Cell membrane; Single-pass type I membrane protein; Extracellular side. Note=Localized at the cell surface of melanoma cells
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
519-548 aa
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靶點(diǎn) |
This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human MMP16.
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亞型 |
Rabbit Ig
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通用名 |
MMPX2
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基因ID |
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UniProt ID |
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功能 |
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
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總結(jié) |
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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圖像 |
MMP16 Antibody (C-term) (Cat. APR03851G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MMP16 antibody detected the MMP16 protein (arrow). MMP16 Antibody (C-term) (Cat. APR03851G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP16 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說(shuō)明書(shū) |
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數(shù)量 |
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