品牌 |
Leading Biology | 貨號(hào) |
APR03847G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HBG1 Antibody (Center).
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分子量 |
16140 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
56-85 aa
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靶點(diǎn) |
This HBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
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總結(jié) |
The gamma globin genes (HBG1 and HBG2) are normallyexpressed in the fetal liver, spleen and bone marrow. Two gammachains together with two alpha chains constitute fetal hemoglobin(HbF) which is normally replaced by adult hemoglobin (HbA) atbirth. In some beta-thalassemias and related conditions, gammachain production continues into adulthood. The two types of gammachains differ at residue 136 where glycine is found in the G-gammaproduct (HBG2) and alanine is found in the A-gamma product (HBG1).The former is predominant at birth. The order of the genes in thebeta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta-- beta--3'.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Western blot analysis of HBG1 (arrow) using rabbit polyclonal HBG1 Antibody (Center) (Cat. APR03847G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HBG1 gene. HBG1 Antibody (Center) (Cat. APR03847G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the HBG1 antibody detected the HBG1 protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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