PRCP Antibody (N-term)

APR03813G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03813G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
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PRCP Antibody (N-term)

品牌	Leading Biology	貨號	APR03813G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRCP Antibody (N-term).
分子量	55800 Da
細胞定位	Antigen Cellular Localization: Lysosome.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	114-143 aa
靶點	This PRCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human PRCP.
亞型	Rabbit Ig
通用名	PCP
基因ID	5547
UniProt ID	P42785
功能	Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
總結(jié)	The protein encoded by this gene is a lysosomalprolylcarboxypeptidase, which cleaves C-terminal amino acids linkedto proline in peptides such as angiotension II, III anddes-Arg9-bradykinin. The cleavage occurs at acidic pH, but theenzyme activity is retained with some substrates at neutral pH.This enzyme has been shown to be an activator of the cellmatrix-associated prekallikrein. The importance of angiotension II,one of the substrates of this enzyme, in regulating blood pressureand electrolyte balance suggests that this gene may be related toessential hypertension. Alternatively spliced transcript variantsencoding distinct isoforms have been observed. [provided byRefSeq].
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
圖像	PRCP Antibody (N-term) (Cat. APR03813G) western blot analysis in MDA-MB231,Hela cell line lysates (35ug/lane).This demonstrates the PRCP antibody detected the PRCP protein (arrow). PRCP Antibody (N-term) (Cat. APR03813G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRCP Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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