SPOPL Antibody (Center)

APR03736G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03736G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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SPOPL Antibody (Center)

品牌	Leading Biology	貨號	APR03736G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPOPL Antibody (Center).
分子量	44647 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	221-249 aa
靶點	This SPOPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of human SPOPL.
亞型	Rabbit Ig
基因ID	339745
UniProt ID	Q6IQ16
功能	Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.
總結(jié)	In complex with a cullin, may act in ubiquitination and proteasomal degradation processes (By similarity).
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	FC, WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50
圖像	SPOPL Antibody (Center) (Cat. APR03736G) western blot analysis in uterus tumor cell line lysates (35ug/lane).This demonstrates the SPOPL antibody detected the SPOPL protein (arrow). SPOPL Antibody (Center) (Cat. APR03736G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SPOPL Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. SPOPL Antibody (Center) (Cat. APR03736G) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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