PSMB10 Antibody (C-term)

APR03711G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03711G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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PSMB10 Antibody (C-term)

品牌	Leading Biology	貨號	APR03711G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSMB10 Antibody (C-term).
分子量	28936 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm {ECO:0000255\|PROSITE- ProRule:PRU00809}. Nucleus
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	214-242 aa
靶點	This PSMB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human PSMB10.
亞型	Rabbit Ig
通用名	LMP10, MECL1
基因ID	5699
UniProt ID	P40306
功能	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.
總結(jié)	The proteasome is a multicatalytic proteinase complex witha highly ordered ring-shaped 20S core structure. The core structureis composed of 4 rings of 28 non-identical subunits; 2 rings arecomposed of 7 alpha subunits and 2 rings are composed of 7 betasubunits. Proteasomes are distributed throughout eukaryotic cellsat a high concentration and cleave peptides in anATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome,is the processing of class I MHC peptides. This gene encodes amember of the proteasome B-type family, also known as the T1Bfamily, that is a 20S core beta subunit. Proteolytic processing isrequired to generate a mature subunit. Expression of this gene isinduced by gamma interferon, and this gene product replacescatalytic subunit 2 (proteasome beta 7 subunit) in theimmunoproteasome.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	All lanes : Anti-PSMB10 Antibody (C-term) at 1:1000 dilution Lane 1: Daudi whole cell lysate Lane 2: Raji whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 29 kDa Blocking/Dilution buffer: 5% NFDM/TBST. PSMB10 Antibody (C-term) (Cat. APR03711G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the PSMB10 antibody detected the PSMB10 protein (arrow).
說明書	Product Datasheet Protocol
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