HYAL2 Antibody (Center)

APR03703G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR03703G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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HYAL2 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR03703G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HYAL2 Antibody (Center).
分子量	53860 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	128-157 aa
靶點(diǎn)	This HYAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human HYAL2.
亞型	Rabbit Ig
通用名	LUCA2
基因ID	8692
UniProt ID	Q12891
功能	Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.
總結(jié)	This gene encodes a weak acid-active hyaluronidase. Theencoded protein is similar in structure to other more activehyaluronidases. Hyaluronidases degrade hyaluronan, one of the majorglycosaminoglycans of the extracellular matrix. Hyaluronan andfragments of hyaluronan are thought to be involved in cellproliferation, migration and differentiation. Although it waspreviously thought to be a lysosomal hyaluronidase that is activeat a pH below 4, the encoded protein is likely a GPI-anchored cellsurface protein. This hyaluronidase serves as a receptor for theoncogenic virus Jaagsiekte sheep retrovirus. The gene is one ofseveral related genes in a region of chromosome 3p21.3 associatedwith tumor suppression. This gene encodes two alternatively splicedtranscript variants which differ only in the 5' UTR.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
圖像	Western blot analysis of HYAL2 Antibody (Center) Pab (Cat. APR03703G) pre-incubated without(lane 1) and with(lane 2) blocking peptide in Hela cell line lysate. HYAL2 Antibody (Center) (arrow) was detected using the purified Pab. HYAL2 Antibody (Center) (Cat. APR03703G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HYAL2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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