全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR03699G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RASAL1 Antibody (Center).
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分子量 |
90016 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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免疫原 |
309-337 aa
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靶點(diǎn) |
This RASAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the Central region of human RASAL1.
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亞型 |
Rabbit Ig
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通用名 |
RASAL
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基因ID |
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UniProt ID |
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功能 |
Probable inhibitory regulator of the Ras-cyclic AMP pathway.
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總結(jié) |
The protein encoded by this gene is member of the GAP1family of GTPase-activating proteins. These proteins stimulate theGTPase activity of normal RAS p21 but not its oncogeniccounterpart. Acting as a suppressor of RAS function, the proteinenhances the weak intrinsic GTPase activity of RAS proteinsresulting in the inactive GDP-bound form of RAS, thereby allowingcontrol of cellular proliferation and differentiation. Thisparticular family member contains domains which are characteristicof the GAP1 subfamily of RasGAP proteins but, in contrast to theother GAP1 family members, this protein is strongly and selectivelyexpressed in endocrine tissues. Alternatively spliced transcriptvariants that encode different isoforms have been described
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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