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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > POMT1 Antibody (C-term)

POMT1 Antibody (C-term)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR03684G 100 μl / ¥4950

POMT1 Antibody (C-term)

品牌

Leading Biology

貨號

APR03684G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality POMT1 Antibody (C-term).

分子量

84881 Da

細(xì)胞定位

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

706-735 aa

靶點(diǎn)

This POMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human POMT1.

亞型

Rabbit Ig

基因ID

UniProt ID

功能

Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient.

總結(jié)

The protein encoded by this gene is anO-mannosyltransferase that requires interaction with the product ofthe POMT2 gene for enzymatic function. The encoded protein is foundin the membrane of the endoplasmic reticulum. Defects in this geneare a cause of Walker-Warburg syndrome (WWS) and limb-girdlemuscular dystrophy type 2K (LGMD2K). Several transcript variantsencoding different isoforms have been found for this gene.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IHC-P, WB, FC, E

稀釋方法

IHC-P~~1:10~50 WB~~1:1000 FC~~1:10~50

圖像

POMT1 Antibody (C-term) (Cat. APR03684G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POMT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

POMT1 Antibody (C-term) (Cat. APR03684G) western blot analysis in ZR-75-1,K562 cell line lysates (35ug/lane).This demonstrates the POMT1 antibody detected the POMT1 protein (arrow).

POMT1 Antibody (C-term) (Cat. APR03684G) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

說明書

數(shù)量

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