SENP2 Antibody (C-term)

APR03675G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03675G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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SENP2 Antibody (C-term)

品牌	Leading Biology	貨號	APR03675G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SENP2 Antibody (C-term).
分子量	67855 Da
細胞定位	Antigen Cellular Localization: Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side Cytoplasm. Note=Shuttles between cytoplasm and nucleus
宿主	Rabbit
種屬反應性	Human, Mouse
免疫原	502-533 aa
靶點	This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.
亞型	Rabbit Ig
通用名	KIAA1331
基因ID	59343
UniProt ID	Q9HC62
功能	Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1.
總結	SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100
圖像	The SENP2 C-term polyclonal antibody (Cat. APR03675G) is used in Western blot to detect SENP2 in mouse heart tissue lysate. Western blot analysis of anti-SENP2 Antibody (C-term)(Cat. APR03675G) in HL60 cell line lysates (35ug/lane). SENP2(arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
說明書	Product Datasheet Protocol
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