品牌 |
Leading Biology |
貨號(hào) |
APR03672G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PDCD1LG2 Antibody (N-term).
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分子量 |
30957 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 3: Secreted. Isoform 1: Cell membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
46-75 aa
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靶點(diǎn) |
This PDCD1LG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human PDCD1LG2.
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亞型 |
Rabbit Ig
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通用名 |
B7DC, CD273, PDCD1L2, PDL2
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基因ID |
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UniProt ID |
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功能 |
Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
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總結(jié) |
PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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圖像 |
All lanes : Anti-PDCD1LG2 Antibody (N-term) at 1:1000-1:2000 dilution
Lane 1: A549 whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Raji whole cell lysate
Lane 4: ZR-75-1 whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 31 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
PDCD1LG2 Antibody (N-term) (Cat. APR03672G) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDCD1LG2 antibody detected the PDCD1LG2 protein (arrow).
PDCD1LG2 Antibody (N-term) (Cat. APR03672G)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PDCD1LG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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說(shuō)明書 |
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數(shù)量 |
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