品牌 |
Leading Biology | 貨號 |
APR03649G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GLMN Antibody (C-term).
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分子量 |
68208 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
498-525 aa
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靶點 |
This GLMN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-525 amino acids from the C-terminal region of human GLMN.
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亞型 |
Rabbit Ig
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通用名 |
FAP48, FAP68, VMGLOM
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基因ID |
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UniProt ID |
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功能 |
Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 production.
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總結(jié) |
This gene encodes a phosphorylated protein that is amember of a Skp1-Cullin-F-box-like complex. The protein isessential for normal development of the vasculature and mutationsin this gene have been associated with glomuvenous malformations,also called glomangiomas. Alternatively spliced variants thatencode different protein isoforms have been described but thefull-length nature of only one has been determined. [provided byRefSeq].
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
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圖像 |
GLMN Antibody (C-term) (Cat. APR03649G) western blot analysis in MDA-MB231,HepG2 cell line lysates (35ug/lane).This demonstrates the GLMN antibody detected the GLMN protein (arrow). GLMN Antibody (C-term) (Cat. APR03649G)immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GLMN Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. GLMN Antibody (C-term) (Cat. APR03649G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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