品牌 |
Leading Biology | 貨號(hào) |
APR03580G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality F11 Antibody (Center).
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分子量 |
70109 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
281-307 aa
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靶點(diǎn) |
This F11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-307 amino acids from the Central region of human F11.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
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總結(jié) |
This gene encodes coagulation factor XI of the bloodcoagulation cascade. This protein is present in plasma as azymogen, which is a unique plasma coagulation enzyme because itexists as a homodimer consisting of two identical polypeptidechains linked by disulfide bonds. During activation of the plasmafactor XI, an internal peptide bond is cleaved by factor XIIa (orXII) in each of the two chains, resulting in activated factor XIa,a serine protease composed of two heavy and two light chains heldtogether by disulfide bonds. This activated plasma factor XItriggers the middle phase of the intrisic pathway of bloodcoagulation by activating factor IX. Defects in this factor lead toRosenthal syndrome, a blood coagulation abnormality. [provided byRefSeq].
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
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圖像 |
All lanes : Anti-F11 Antibody (Center) at 1:1000 dilution Lane 1: A549 whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 70 kDa Blocking/Dilution buffer: 5% NFDM/TBST. F11 Antibody (Center) (Cat. APR03580G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F11 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說(shuō)明書(shū) |
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數(shù)量 |
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