IRF2 Antibody (Center)

APR03541G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR03541G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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IRF2 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR03541G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRF2 Antibody (Center).
分子量	39354 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	225-255 aa
靶點(diǎn)	This IRF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from the Central region of human IRF2.
亞型	Rabbit Ig
基因ID	3660
UniProt ID	P14316
功能	Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
總結(jié)	IRF2 encodes interferon regulatory factor 2, a member ofthe interferon regulatory transcription factor (IRF) family. IRF2competitively inhibits the IRF1-mediated transcriptional activationof interferons alpha and beta, and presumably other genes thatemploy IRF1 for transcription activation. However, IRF2 alsofunctions as a transcriptional activator of histone H4. [providedby RefSeq].
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	Anti-IRF2 Antibody (Center) at 1:1000 dilution + LNCaP whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST. IRF2 Antibody (Center) (Cat. APR03541G) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the IRF2 antibody detected the IRF2 protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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