品牌 |
Leading Biology | 貨號(hào) |
APR03518G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality WDR51B Antibody (C-term).
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分子量 |
53668 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles Localizes to the basal body and centriole adjacent to the connecting cilium of photoreceptors and in synapses of the outer plexiform layer. {ECO:0000250|UniProtKB:Q8BHD1}
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
321-350 aa
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靶點(diǎn) |
This WDR51B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-350 amino acids from the C-terminal region of human WDR51B.
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亞型 |
Rabbit Ig
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通用名 |
WDR51B
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基因ID |
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UniProt ID |
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功能 |
Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745).
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總結(jié) |
Required for ciliogenesis.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
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圖像 |
Western blot analysis of WDR51B Antibody (C-term) Pab (Cat. APR03518G) pre-incubated without(lane 1) and with(lane 2) blocking peptide in MDA-MB453 cell line lysate. WDR51B Antibody (C-term) (arrow) was detected using the purified Pab. WDR51B antibody (C-term) (Cat. APR03518G) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the WDR51B antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說(shuō)明書 |
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數(shù)量 |
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