品牌 |
Leading Biology | 貨號 |
APR03510G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BCLAF1 Antibody (C-term).
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分子量 |
106122 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
658-687 aa
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靶點 |
This BCLAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human BCLAF1.
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亞型 |
Rabbit Ig
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通用名 |
BTF, KIAA0164
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基因ID |
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UniProt ID |
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功能 |
Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
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總結(jié) |
This gene encodes a transcriptional repressor thatinteracts with several members of the BCL2 family of proteins.Overexpression of this protein induces apoptosis, which can besuppressed by co-expression of BCL2 proteins. The protein localizesto dot-like structures throughout the nucleus, and redistributes toa zone near the nuclear envelope in cells undergoing apoptosis.Multiple transcript variants encoding different isoforms have beenfound for this gene.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
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圖像 |
BCLAF1 Antibody (C-term) (Cat. APR03510G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the BCLAF1 antibody detected the BCLAF1 protein (arrow). BCLAF1 antibody (C-term) (Cat. APR03510G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCLAF1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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