ZC12A Antibody (Center)

APR03508G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03508G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ZC12A Antibody (Center)

品牌	Leading Biology	貨號	APR03508G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZC12A Antibody (Center).
分子量	65699 Da
細胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus
宿主	Rabbit
種屬反應性	Human
免疫原	331-358 aa
靶點	This ZC12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 amino acids from the Central region of human ZC12A.
亞型	Rabbit Ig
基因ID	80149
UniProt ID	Q5D1E8
功能	Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.
總結(jié)	ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein thatacts as a transcriptional activator and causes cell death ofcardiomyocytes, possibly via induction of genes associated withapoptosis.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
圖像	ZC12A Antibody (Center) (Cat. APR03508G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ZC12A antibody detected the ZC12A protein (arrow). ZC12A antibody (Center) (Cat. APR03508G) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZC12A antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. ZC12A Antibody (Center) (Cat. APR03508G) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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