品牌 |
Leading Biology | 貨號 |
APR03500G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD2BP2 Antibody (N-term).
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分子量 |
37646 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Predominantly nuclear
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
24-52 aa
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靶點 |
This CD2BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human CD2BP2.
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亞型 |
Rabbit Ig
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通用名 |
KIAA1178
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基因ID |
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UniProt ID |
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功能 |
Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
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總結 |
This gene encodes a bi-functional protein. In thecytoplasm, the encoded protein binds the cytoplasmic tail of humansurface antigen CD2 via its C-terminal GYF domain, and regulateCD2-triggered T lymphocyte activation. In the nucleus, this proteinis a component of the U5 small nuclear ribonucleoprotein complexand is involved in RNA splicing. A pseudogene has been identifiedon chromosome 7. Alternative splicing results in multipletranscript variants but their biological validity has not beendetermined.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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圖像 |
CD2BP2 Antibody (N-term) (Cat. APR03500G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD2BP2 antibody detected the CD2BP2 protein (arrow). CD2BP2 antibody(N-term) (Cat. APR03500G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CD2BP2 antibody(N-term) for immunohistochemistry. Clinical relevance has not been evaluated. CD2BP2 Antibody (N-term) (Cat. APR03500G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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