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Polyclonal Antibodies >
FKBP8 / FKBP38 Antibody (internal region)品牌 |
Leading Biology | 貨號(hào) |
APG00543G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FKBP8 / FKBP38 Antibody (internal region).
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分子量 |
44562 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Mitochondrion membrane; Single- pass membrane protein; Cytoplasmic side
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宿主 |
Goat
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亞型 |
IgG
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通用名 |
FKBP38
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基因ID |
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UniProt ID |
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功能 |
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
E
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說(shuō)明書 |
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數(shù)量 |
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