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Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Antibody品牌 |
Leading Biology | 貨號(hào) |
APR14592G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) antibody.
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分子量 |
40-56.5kDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Monkey, Chicken, Cow, Dog
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克隆號(hào) |
AE-1
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亞型 |
Mouse / IgG1, kappa
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通用名 |
KRT1B
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基因ID |
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UniProt ID |
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總結(jié) |
This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50ā€?, 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, FC
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別名 |
Keratin, type II cytoskeletal 1b, Cytokeratin-1B, CK-1B, Keratin-77, K77, Type-II keratin Kb39, KRT77, KRT1B
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圖像 |
Formalin-fixed, paraffin-embedded human Skin stained with Cytokeratin, LMW Monoclonal Antibody (AE-1) Western Blot of A431 Cells using Cytokeratin, LMW Monoclonal Antibody (AE-1). |
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說(shuō)明書(shū) |
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數(shù)量 |
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