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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody品牌 |
Leading Biology | 貨號 |
APR14602G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) antibody.
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分子量 |
67kDa (CK1); 58kDa (CK5); 56.5kDa (CK10); 50kDa (CK14)
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane. Note=Located on plasma membrane of neuroblastoma NMB7 cells
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat
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克隆號 |
SPM591
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亞型 |
Mouse / IgG1, kappa
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通用名 |
KRTA
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基因ID |
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UniProt ID |
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功能 |
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
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總結(jié) |
This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, FC
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別名 |
Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA
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圖像 |
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說明書 |
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數(shù)量 |
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