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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CYP1A1 Antibody (C-term) (Ascites)

CYP1A1 Antibody (C-term) (Ascites)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG02870G 0.1 ml / ¥4950

CYP1A1 Antibody (C-term) (Ascites)

品牌

Leading Biology

貨號(hào)

APG02870G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP1A1 antibody (C-term) (Ascites).

分子量

58165 Da

細(xì)胞定位

Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein

宿主

Mouse

種屬反應(yīng)性

Human

免疫原

377-405 aa

靶點(diǎn)

This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1.

克隆號(hào)

655CT6.1.2

亞型

IgG1

基因ID

UniProt ID

功能

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

總結(jié)

This gene, CYP1A1, encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and itsexpression is induced by some polycyclic aromatic hydrocarbons(PAHs), some of which are found in cigarette smoke. The enzyme'sendogenous substrate is unknown; however, it is able to metabolizesome PAHs to carcinogenic intermediates. The gene has beenassociated with lung cancer risk. A related family member, CYP1A2,is located approximately 25 kb away from CYP1A1 on chromosome 15.

形式

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:500~4000

別名

Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, CYP1A1

圖像

CYP1A1 Antibody (C-term)(Ascites)(Cat. APG02870G) western blot analysis in 293 cell line lysates (35μg/lane).This demonstrates the CYP1A1 antibody detected the CYP1A1 protein (arrow).

說(shuō)明書

數(shù)量

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