CYP2C9 Antibody (N-term) (Ascites)

APG02887G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG02887G		0.1 ml / ￥4950

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安諾倫（北京）生物科技有限公司

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CYP2C9 Antibody (N-term) (Ascites)

品牌	Leading Biology	貨號	APG02887G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP2C9 antibody (N-term) (Ascites).
分子量	55628 Da
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	82-110 aa
靶點(diǎn)	This CYP2C9 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of human CYP2C9.
克隆號	682CT5.6.2
亞型	IgM
通用名	CYP2C10
基因ID	1559
UniProt ID	P11712
功能	Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S- warfarin, diclofenac, phenytoin, tolbutamide and losartan.
總結(jié)	This gene encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and itsexpression is induced by rifampin. The enzyme is known tometabolize many xenobiotics, including phenytoin, tolbutamide,ibuprofen and S-warfarin. Studies identifying individuals who arepoor metabolizers of phenytoin and tolbutamide suggest that thisgene is polymorphic. The gene is located within a cluster ofcytochrome P450 genes on chromosome 10q24.
形式	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:100~1600
別名	Cytochrome P450 2C9, 11413-, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC9, Cytochrome P-450MP, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 PB-1, S-mephenytoin 4-hydroxylase, CYP2C9, CYP2C10
圖像	CYP2C9 Antibody (N-term)(Ascites)(Cat. APG02887G) western blot analysis in NCI-H460 cell line lysates (35μg/lane).This demonstrates the CYP2C9 antibody detected the CYP2C9 protein (arrow).
說明書	Product Datasheet Protocol
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