全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APG02869G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CYP1A1 antibody (C-term).
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分子量 |
58165 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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免疫原 |
377-405 aa
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靶點(diǎn) |
This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1.
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克隆號(hào) |
655CT6.1.2
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
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總結(jié) |
This gene, CYP1A1, encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and itsexpression is induced by some polycyclic aromatic hydrocarbons(PAHs), some of which are found in cigarette smoke. The enzyme'sendogenous substrate is unknown; however, it is able to metabolizesome PAHs to carcinogenic intermediates. The gene has beenassociated with lung cancer risk. A related family member, CYP1A2,is located approximately 25 kb away from CYP1A1 on chromosome 15.
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形式 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, CYP1A1
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圖像 |
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說明書 |
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數(shù)量 |
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