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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Prealbumin Antibody

Prealbumin Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APR12960G 100 μl / ¥5450

Prealbumin Antibody

品牌

Leading Biology

貨號

APR12960G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Prealbumin antibody.

分子量

15887 Da

細胞定位

Antigen Cellular Localization: Secreted. Cytoplasm.

宿主

Rabbit

種屬反應(yīng)性

Human

靶點

A synthetic peptide corresponding to residues in human Prealbumin was used as an immunogen.

克隆號

EPR3219

通用名

PALB

基因ID

UniProt ID

功能

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

總結(jié)

Prealbumin (TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). Prealbumin concentrations are disproportionately high in human ventricular cerebrospinal fluid (CSF). It is reported to be either selectively transported across or synthesized within the blood-CSF barrier (3). Over 80 different disease-causing mutations in prealbumin have been reported. The vast majority is inherited in an autosomal dominant manner and is related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. A small portion of prealbumin mutations are apparently non-amyloidogenic (4). The human amyloid disorders, familial amyloid polyneuropathy, familial amyloid cardiomyopathy and senile systemic amyloidosis, are caused by insoluble prealbumin fibrils (2).

形式

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC

稀釋方法

WB~~1:1000~5000 IHC~~1:100~250

別名

Transthyretin, ATTR, Prealbumin, TBPA, TTR, PALB

圖像

A. Western blot analysis on (A) human plasma and (B) human placenta lysates using anti-Prealbumin RabMAb (Cat. APR12960G), dilution 1:5000.

B. Immunohistochemical analysis of paraffin-embedded human liver using anti-Prealbumin RabMAb (Cat. APR12960G).

說明書

數(shù)量

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