Prealbumin Antibody

APR12961G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR12961G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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Prealbumin Antibody

品牌	Leading Biology	貨號(hào)	APR12961G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Prealbumin antibody.
分子量	15887 Da
細(xì)胞定位	Antigen Cellular Localization: Secreted. Cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	A synthetic peptide corresponding to residues on the C-terminus of human Prealbumin was used as an immunogen.
克隆號(hào)	EP2929Y
通用名	PALB
基因ID	7276
UniProt ID	P02766
功能	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
總結(jié)	Transthyretin (prealbumin/TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). Transthyretin concentrations are disproportionately high in human ventricular CSF. It is reported to be either selectively transported across or synthesized within the blood-CSF barrier (3). Over 80 different disease-causing mutations in transthyretin have been reported. The vast majority is inherited in an autosomal dominant manner and is related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. A small portion of transthyretin mutations are apparently non-amyloidogenic (4). The human amyloid disorders, familial amyloid polyneuropathy, familial amyloid cardiomyopathy and senile systemic amyloidosis, are caused by insoluble transthyretin fibrils (2). Transthyretin has a structural complementarity to double-helical DNA, where the proposed binding site is composed of two symmetry-related beta-sheets containing a pair of helically disposed arms (1).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
稀釋方法	WB~~1:1000~10000 IHC~~1:250~500
別名	Transthyretin, ATTR, Prealbumin, TBPA, TTR, PALB
圖像	A.Western blot analysis on (A) human heart, (B) human placenta and (C) human brain lysates using anti-PrealbuminRabMAb (Cat. APR12961G), dilution 1:5000. B. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Prealbumin RabMAb (Cat. APR12961G).
說明書	Product Datasheet Protocol
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