CDX2 Antibody

APR15381G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR15381G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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CDX2 Antibody

品牌	Leading Biology	貨號(hào)	APR15381G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDX2 antibody.
分子量	33520 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	A synthetic peptide corresponding to residues near the N-terminus of human CDX-2 was used as an immunogen.
克隆號(hào)	EPR2764Y
通用名	CDX3
基因ID	1045
UniProt ID	Q99626
功能	Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
總結(jié)	The caudal-related homeodomain protein 2, CDX-2, is a transcription factor which is expressed in the intestine and is thought to play an important role in the proliferation and differentiation of intestinal epithelial cells. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer. In human colorectal cancer, the expression of both CDX2 and carbonic anhydrase 1, a gene regulated by CDX2, is reduced or absent. (1). CDX-2 is one of the important regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract (2).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
稀釋方法	WB~~1:2000 IHC~~1:250~500
別名	Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3
圖像	A. Western blot analysis on (A) HT29, (B) colon cancer and (C) human small intestine lysates using anti-CDX-2 RabMAb (Cat. APR15381G), dilution (A) 1:1000 and (B, C) 1:5000. B. Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma using anti-CDX-2 RabMAb (Cat. APR15381G).
說明書	Product Datasheet Protocol
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