品牌 |
Leading Biology | 貨號 |
APG02562G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CGA antibody.
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分子量 |
13075 Da
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細胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
A synthetic peptide corresponding to residues at the C terminus of human CGA was used as an immunogen.
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克隆號 |
EP3373
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基因ID |
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UniProt ID |
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總結(jié) |
CGA belongs to the glycoprotein hormone alpha chain family that includes the alpha subunit of chronic gonadotropin (CG), lutenizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH). The glycoprotein hormones have the most complex chemical structures of the classical protein hormones. They are dimers consisting of alpha and beta subunits that are associated noncovalently (1, 4). The alpha subunit is common to all of the hormones; however, their beta chains are unique and confer biological specificity (1). These hormones are central to the complex endocrine system that regulates normal growth, sexual development, and reproductive function (2). The hormones LH, FSH and TSH are secreted by the anterior pituitary gland, while CG is secreted by the placenta (3).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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稀釋方法 |
WB~~1:500~1000
IHC~~1:100~250
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別名 |
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain, CGA
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圖像 |
Western blot analysis on JAR cell lysates using anti-CGA RabMAb (Cat. APG02562G). Cells were either (A) treated with Hydroxyurea or (B) untreated. Immunohistochemical analysis of paraffin-embedded placenta using anti-CGA RabMAb (Cat. APG02562G). |
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說明書 |
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數(shù)量 |
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