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當(dāng)前位置：首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > KCa3.1 (SK4) (extracellular) Antibody

KCa3.1 (SK4) (extracellular) Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM06066G 50 μg / ￥5450

KCa3.1 (SK4) (extracellular) Antibody

品牌

 Leading Biology

貨號(hào)

 AMM06066G

產(chǎn)品分類

 Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCa3.1 (SK4) (extracellular) antibody.

分子量
47696 Da

宿主
Mouse

種屬反應(yīng)性
Human, Mouse

基因ID

UniProt ID

總結(jié)
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.

形式
Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC, FC, ICC

別名
Intermediate conductance calcium-activated potassium channel protein 4, SK4, SKCa 4, SKCa4, IKCa1, IK1, KCa3.1, KCa4, Putative Gardos channel, KCNN4, IK1, IKCA1, KCA4, SK4

圖像

Western blot analysis using Anti-KCa3.1 (SK4) (extracellular) mouse monoclonal antibody ( AMM06066G), (1:250):1. HEK cells transfected with control vector.2. HEK cells transfected with human KCa3.1.

Western blot analysis using Anti-KCa3.1 (SK4) (extracellular) mouse monoclonal antibody ( AMM06066G), (1:250):1. Mouse MS1 endothelial cells.2. Rat IEC-6 intestinal epithelial cells.3. Human LN-CaP prostate carcinoma cells.4. Human THP-1 acute monocytic leukemia cells.

Immuno-colocalization of KCa3.1 and TRPC1 in mouse brain Immunohistochemical staining of mouse brain sections using Anti-KCa3.1 (SK4) (extracellular) mouse monoclonal antibody ( AMM06066G) and Anti-TRPC1 antibody ( ACC-010). TRPC1 staining (blue) is detected in neuroblasts and outside neuroblasts as well (in astrocytes). KCa3.1 (red) is detected in neuroblasts. Merged image demonstrates the partial co-localization between the two.Adapted from Turner, K.L. et al. (2013) Cereb. Cortex 24, 2388. with permission of Oxford University Press.

說明書

數(shù)量

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