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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Glutathione Peroxidase 1 Antibody (Clone 2A10)

Glutathione Peroxidase 1 Antibody (Clone 2A10)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMRa00026G 100 μl / ¥5450

Glutathione Peroxidase 1 Antibody (Clone 2A10)

品牌

Leading Biology

貨號

AMRa00026G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Glutathione Peroxidase 1 antibody (Clone 2A10).

分子量

22088 Da

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm.

宿主

Mouse

種屬反應(yīng)性

Human

靶點(diǎn)

Glutathione Peroxidase 1

克隆號

Clone 2A10

亞型

Mouse IgG1

基因ID

UniProt ID

功能

Protects the hemoglobin in erythrocytes from oxidative breakdown.

總結(jié)

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic /mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IP

別名

GPX1

圖像

IP analysis of HL60 cell lysates. Lane 1: Input, Lane 2: Precipitated sample

說明書

數(shù)量

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