BANF1 / BAF / BCRP1 Antibody (clone 3F10-4G12)

APR11005G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR11005G		50 μg / ￥5450

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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BANF1 / BAF / BCRP1 Antibody (clone 3F10-4G12)

品牌	Leading Biology	貨號(hào)	APR11005G
產(chǎn)品分類(lèi)	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BANF1 / BAF / BCRP1 antibody (clone 3F10-4G12).
分子量	10kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Chromosome. Note=Significantly enriched at the nuclear inner membrane, diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase May be included in HIV-1 virions via its interaction with viral GAG polyprotein. The phosphorylated form (by VRK1) shows a cytoplasmic localization
宿主	Mouse
種屬反應(yīng)性	Human
克隆號(hào)	3F10-4G12
通用名	BAF, BCRG1
基因ID	8815
UniProt ID	O75531
功能	Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
總結(jié)	Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	IHC-P (5 μg/ml)
別名	Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor, N-terminally processed, BANF1, BAF, BCRG1
圖像	BANF1 monoclonal antibody, clone 3F10-4G12 Western blot of BANF1 expression in Jurkat. Anti-BANF1 antibody IHC of human colon. Anti-BANF1 antibody IHC of human testis.
說(shuō)明書(shū)	Product Datasheet Protocol
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BANF1 / BAF / BCRP1 Antibody (clone 3F10-4G12)