KPNA2 Antibody

APR17025G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR17025G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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KPNA2 Antibody

品牌	Leading Biology	貨號	APR17025G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KPNA2 antibody.
分子量	58kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus
宿主	Mouse
種屬反應(yīng)性	Human, Mouse
克隆號	1E8B7
亞型	IgG1
通用名	RCH1, SRP1
基因ID	3838
UniProt ID	P52292
功能	Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, FC, ICC, E
稀釋方法	E~~1/10000 WB~~1/500 - 1/2000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000
別名	Importin subunit alpha-1, Karyopherin subunit alpha-2, RAG cohort protein 1, SRP1-alpha, KPNA2, RCH1, SRP1
圖像	Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Figure 2:Western blot analysis using KPNA2 mAb against human KPNA2 (AA: 1-530) recombinant protein. (Expected MW is 60.3 kDa) Figure 3:Western blot analysis using KPNA2 mAb against HEK293 (1) and KPNA2 (AA: 1-530)-hIgGFc transfected HEK293 (2) cell lysate.
說明書	Product Datasheet Protocol
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