全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR10447G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality THAP1 antibody.
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分子量 |
24.9kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus, nucleoplasm. Nucleus, PML body
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
8D10C8
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, FC, ICC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
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別名 |
THAP domain-containing protein 1, THAP1
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圖像 |
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說明書 |
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數(shù)量 |
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