NOX4 Antibody

APR08785G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR08785G		100 μl / ￥5450

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NOX4 Antibody

品牌	Leading Biology	貨號	APR08785G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NOX4 antibody.
分子量	67kDa
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell junction, focal adhesion. Note=May localize to plasma membrane and focal adhesions. According to PubMed:15927447, may also localize to the nucleus
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	3H2C4
亞型	IgG1
通用名	RENOX
基因ID	50507
UniProt ID	Q9NPH5
功能	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, FC, ICC, E
稀釋方法	E~~1/10000 WB~~1/500 - 1/2000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000
別名	NADPH oxidase 4, 1.6.3.-, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, NOX4, RENOX
圖像	Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 2:Western blot analysis using NOX4 mAb against human NOX4 (AA: 210-310) recombinant protein. (Expected MW is 25.3 kDa) Figure 3:Western blot analysis using NOX4 mAb against HEK293 (1) and NOX4 (AA: 210-310)-hIgGFc transfected HEK293 (2) cell lysate.
說明書	Product Datasheet Protocol
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