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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > MAP1LC3B Antibody

MAP1LC3B Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR12502G 100 μl / ¥5450

MAP1LC3B Antibody

品牌

Leading Biology

貨號(hào)

APR12502G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP1LC3B antibody.

分子量

14.6kDa

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes Localizes also to discrete punctae along the ciliary axoneme (By similarity).

宿主

Mouse

種屬反應(yīng)性

Human

克隆號(hào)

5H12

亞型

IgG1

通用名

MAP1ALC3

基因ID

UniProt ID

功能

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, FC, E

稀釋方法

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400

別名

Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B, Microtubule-associated protein 1 light chain 3 beta, MAP1LC3B, MAP1ALC3

圖像

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using MAP1LC3B mAb against human MAP1LC3B (AA: 1-125) recombinant protein. (Expected MW is 40.2 kDa)

Figure 2: Western blot analysis using MAP1LC3B mAb against HEK293 (1) and MAP1LC3B (AA: 1-125)-hIgGFc transfected HEK293 (2) cell lysate.

說明書

數(shù)量

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