品牌 |
Leading Biology |
貨號(hào) |
APR17073G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KRT18 / CK18 / Cytokeratin 18 antibody (clone RCK106).
|
分子量 |
48kDa
|
細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, perinuclear region. Nucleus, nucleolus
|
宿主 |
Mouse
|
種屬反應(yīng)性 |
Human
|
靶點(diǎn) |
Reacts exclusively with cytokeratin 18 in glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells, as well as adenocarcinomas originating from them. Reacts exclusively with human.
|
克隆號(hào) |
RCK106
|
通用名 |
CYK18
|
基因ID |
|
UniProt ID |
|
功能 |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
|
總結(jié) |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
|
形式 |
Liquid
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, IHC-P, ICC, IHC-Fr, Flo
|
稀釋方法 |
Flo (1:100-1:200), IHC-Fr (1:100-1:200), IHC-P (10 μg/ml), WB (1:100-1:1000) ,
|
別名 |
Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
|
圖像 |
Anti-KRT18 / Cytokeratin 18 antibody IHC of human lung, respiratory epithelium.
|
說明書 |
|
數(shù)量 |
|