ADA Antibody (C-term)

APG01543G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APG01543G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
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ADA Antibody (C-term)

品牌	Leading Biology	貨號	APG01543G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADA antibody (C-term).
分子量	H=41 KDa
細胞定位	Antigen Cellular Localization: Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	287-314 aa
靶點	This ADA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the C-terminal region of human ADA.
通用名	ADA1
基因ID	100
UniProt ID	P00813
功能	Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion.
總結(jié)	This gene encodes an enzyme that catalyzes the hydrolysisof adenosine to inosine. Various mutations have been described forthis gene and have been linked to human diseases. Deficiency inthis enzyme causes a form of severe combined immunodeficiencydisease (SCID), in which there is dysfunction of both B and Tlymphocytes with impaired cellular immunity and decreasedproduction of immunoglobulins, whereas elevated levels of thisenzyme have been associated with congenital hemolytic anemia.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB
稀釋方法	WB~~1:4000
別名	Adenosine deaminase, Adenosine aminohydrolase, ADA, ADA1
圖像	All lanes : Anti-ADA Antibody (C-term) at 1:4000 dilution Lane 1: Jurkat whole cell lysate Lane 2: MOLT-4 whole cell lysate Lane 3: CCRF-CEM whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
說明書	Product Datasheet Protocol
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